Forskolin    reference

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Despite the odd name, Forskolin is not what they remove from the baby during ritual circumcision

The herb Coleus forskohlii is used by the Hindu traditional medicine to treat asthma, heart disease and more. The small mint-family herb is also found in Sri Lanka, Thailand, and Nepal.

In the 1970s,  a chemically active ingredient called Forskolin was isolated from the herb . Now available in supplement form, this extract is commonly recommended for treating hypothyroidism, a condition in which the thyroid gland produces too little thyroid hormone. Forskolin is believed to stimulate the release of thyroid hormone, thus relieving such hypothyroidism symptoms as fatigue, depression, weight gain, and dry skin.
Specifically, forskolin is thought to increase thyroid function by activating an enzyme that raises levels of a key cell-regulating substance called cAMP (cyclic adenosine monophosphate).,1525,10025,00.html#What_Is_It

Forskolin may be helpful to control the underlying cause of glaucoma. The sometimes successful use of forskolin to reduce intraocular pressure may be due to its unique ability to stimulate adenylate cyclase activity and increase cyclic adenosine monophosphate (cAMP) which regulates and activates critical enzymes required for the cellular energy required to move fluid out of the eye

To date, there have been two clinical studies examining the effectiveness of forskolin as a weight loss aid. Neither have yet been subject to peer-review or published in a medical journal. Additionally, according to the company that manufactures and administers the patented form of forskolin, two more clinical studies are being sponsored. Research update, June 2001.



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* The diterpene forskolin was isolated for its pronounced biological activities.




[top] This page was done by a student of Bioinformatics, Open University Jerusalem Israel, in a homage to Fermentek and to Dr Berend.
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